HERC1-SNX6 Fusion FISH Probe
The HERC1-SNX6 Fusion FISH Probe is used to confirm a fusion of the HERC1 and SNX6 genes. The fusion of the HERC1 and SNX6 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HERC1-SNX6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-RERE | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-REOR | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-REGO | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-REGR | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-REAQ | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-ORRE | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-OROR | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-ORGO | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-ORAQ | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-GORE | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-GOOR | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-GOGO | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-GOGR | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-GOAQ | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-GRRE | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-GROR | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-GRGO | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-GRGR | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-GRAQ | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-AQRE | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-AQOR | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-AQGO | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-AQGR | 20 (40 μL) | 200 μL |
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| HERC1-SNX6-20-AQAQ | 20 (40 μL) | 200 μL |
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HERC1 Gene Summary
This gen encodes a member of the HERC protein family. This protein stimulates guanine nucleotide exchange on ARF1 and Rab proteins. This protein may be involved in membrane transport processes. [provided by RefSeq, Mar 2012]
Gene Name: HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 1
Chromosome: CHR15: 63900816 -64126147
Locus: 15q22.31
SNX6 Gene Summary
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Sorting Nexin 6
Chromosome: CHR14: 35030617 -35099366
Locus: 14q13.1
Gene Diseases
The HERC1 SNX6 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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