HERC1-DAPK2 Fusion FISH Probe
The HERC1-DAPK2 Fusion FISH Probe is used to confirm a fusion of the HERC1 and DAPK2 genes. The fusion of the HERC1 and DAPK2 genes has been associated with Breast Invasive Carcinoma, Bladder Urothelial Carcinoma, Liver Hepatocellular Carcinoma, Adrenocortical Carcinoma, and Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HERC1-DAPK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-RERE | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-REOR | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-REGO | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-REGR | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-REAQ | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-ORRE | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-OROR | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-ORGO | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-GORE | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-GOOR | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-GOGO | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-GOGR | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-GRRE | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-GROR | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-GRGO | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-GRGR | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-AQRE | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-AQOR | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-AQGO | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-AQGR | 20 (40 μL) | 200 μL |
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| HERC1-DAPK2-20-AQAQ | 20 (40 μL) | 200 μL |
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HERC1 Gene Summary
This gen encodes a member of the HERC protein family. This protein stimulates guanine nucleotide exchange on ARF1 and Rab proteins. This protein may be involved in membrane transport processes. [provided by RefSeq, Mar 2012]
Gene Name: HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase Family Member 1
Chromosome: CHR15: 63900816 -64126147
Locus: 15q22.31
DAPK2 Gene Summary
This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. [provided by RefSeq, Jul 2008]
Gene Name: Death Associated Protein Kinase 2
Chromosome: CHR15: 64199234 -64338521
Locus: 15q22.31
Gene Diseases
The HERC1 DAPK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
| Bladder Urothelial Carcinoma |
| Liver Hepatocellular Carcinoma |
| Adrenocortical Carcinoma |
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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