HEPHL1-GUCY1A2 Fusion FISH Probe
The HEPHL1-GUCY1A2 Fusion FISH Probe is used to confirm a fusion of the HEPHL1 and GUCY1A2 genes. The fusion of the HEPHL1 and GUCY1A2 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HEPHL1-GUCY1A2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-RERE | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-REOR | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-REGO | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-REGR | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-REAQ | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-ORRE | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-OROR | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-ORGO | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-ORAQ | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-GORE | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-GOOR | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-GOGO | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-GOGR | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-GOAQ | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-GRRE | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-GROR | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-GRGO | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-GRGR | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-GRAQ | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-AQRE | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-AQOR | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-AQGO | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-AQGR | 20 (40 μL) | 200 μL |
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| HEPHL1-GUCY1A2-20-AQAQ | 20 (40 μL) | 200 μL |
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GUCY1A2 Gene Summary
Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Name: Guanylate Cyclase 1 Soluble Subunit Alpha 2
Chromosome: CHR11: 106557909 -106889171
Locus: 11q22.3
HEPHL1 Gene Summary
The Hephaestin Like 1 (HEPHL1) gene is located on chr11 :93754377-93847374 at 11q21.
Gene Name: Hephaestin Like 1
Chromosome: CHR11: 93754377 -93847374
Locus: 11q21
Gene Diseases
The HEPHL1 GUCY1A2 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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