HELZ-TAF15 Fusion FISH Probe
The HELZ-TAF15 Fusion FISH Probe is used to confirm a fusion of the HELZ and TAF15 genes. The fusion of the HELZ and TAF15 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HELZ-TAF15-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-RERE | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-REOR | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-REGO | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-REGR | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-REAQ | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-ORRE | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-OROR | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-ORGO | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-ORAQ | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-GORE | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-GOOR | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-GOGO | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-GOGR | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-GOAQ | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-GRRE | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-GROR | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-GRGO | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-GRGR | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-GRAQ | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-AQRE | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-AQOR | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-AQGO | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-AQGR | 20 (40 μL) | 200 μL |
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| HELZ-TAF15-20-AQAQ | 20 (40 μL) | 200 μL |
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TAF15 Gene Summary
This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Gene Name: TATA-box Binding Protein Associated Factor 15
Chromosome: CHR17: 34136487 -34174238
Locus: 17q12
HELZ Gene Summary
HELZ is a member of the superfamily I class of RNA helicases. RNA helicases alter the conformation of RNA by unwinding double-stranded regions, thereby altering the biologic activity of the RNA molecule and regulating access to other proteins (Wagner et al., 1999 [PubMed 10471385]).[supplied by OMIM, Mar 2008]
Gene Name: Helicase With Zinc Finger
Chromosome: CHR17: 65066553 -65241319
Locus: 17q24.2
Gene Diseases
The HELZ TAF15 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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