HECTD2-GLRX3 Fusion FISH Probe
The HECTD2-GLRX3 Fusion FISH Probe is used to confirm a fusion of the HECTD2 and GLRX3 genes. The fusion of the HECTD2 and GLRX3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HECTD2-GLRX3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-RERE | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-REOR | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-REGO | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-REGR | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-REAQ | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-ORRE | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-OROR | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-ORGO | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-ORAQ | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-GORE | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-GOOR | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-GOGO | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-GOGR | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-GOAQ | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-GRRE | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-GROR | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-GRGO | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-GRGR | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-GRAQ | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-AQRE | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-AQOR | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-AQGO | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-AQGR | 20 (40 μL) | 200 μL |
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| HECTD2-GLRX3-20-AQAQ | 20 (40 μL) | 200 μL |
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GLRX3 Gene Summary
This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
Gene Name: Glutaredoxin 3
Chromosome: CHR10: 131934638 -131978646
Locus: 10q26.3
HECTD2 Gene Summary
The HECT Domain E3 Ubiquitin Protein Ligase 2 (HECTD2) gene is located on chr10 :93170095-93274520 at 10q23.32.
Gene Name: HECT Domain E3 Ubiquitin Protein Ligase 2
Chromosome: CHR10: 93170095 -93274520
Locus: 10q23.32
Gene Diseases
The HECTD2 GLRX3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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