HDLBP-SMARCE1 Fusion FISH Probe
The HDLBP-SMARCE1 Fusion FISH Probe is used to confirm a fusion of the HDLBP and SMARCE1 genes. The fusion of the HDLBP and SMARCE1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HDLBP-SMARCE1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-RERE | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-REOR | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-REGO | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-REGR | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-REAQ | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-ORRE | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-OROR | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-ORGO | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-ORAQ | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-GORE | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-GOOR | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-GOGO | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-GOGR | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-GOAQ | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-GRRE | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-GROR | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-GRGO | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-GRGR | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-GRAQ | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-AQRE | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-AQOR | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-AQGO | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-AQGR | 20 (40 μL) | 200 μL |
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| HDLBP-SMARCE1-20-AQAQ | 20 (40 μL) | 200 μL |
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HDLBP Gene Summary
The protein encoded by this gene binds high density lipoprotein (HDL) and may function to regulate excess cholesterol levels in cells. The encoded protein also binds RNA and can induce heterochromatin formation. [provided by RefSeq, Mar 2016]
Gene Name: High Density Lipoprotein Binding Protein
Chromosome: CHR2: 242166681 -242255115
Locus: 2q37.3
SMARCE1 Gene Summary
The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq, Jul 2008]
Gene Name: SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily E, Member 1
Chromosome: CHR17: 38783975 -38804103
Locus: 17q21.2
Gene Diseases
The HDLBP SMARCE1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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