HDAC9-SNX10 Fusion FISH Probe
The HDAC9-SNX10 Fusion FISH Probe is used to confirm a fusion of the HDAC9 and SNX10 genes. The fusion of the HDAC9 and SNX10 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HDAC9-SNX10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-RERE | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-REOR | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-REGO | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-REGR | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-REAQ | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-ORRE | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-OROR | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-ORGO | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-ORAQ | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-GORE | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-GOOR | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-GOGO | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-GOGR | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-GOAQ | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-GRRE | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-GROR | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-GRGO | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-GRGR | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-GRAQ | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-AQRE | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-AQOR | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-AQGO | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-AQGR | 20 (40 μL) | 200 μL |
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| HDAC9-SNX10-20-AQAQ | 20 (40 μL) | 200 μL |
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HDAC9 Gene Summary
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Histone Deacetylase 9
Chromosome: CHR7: 18126571 -18708466
Locus: 7p21.1
SNX10 Gene Summary
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. This gene may play a role in regulating endosome homeostasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
Gene Name: Sorting Nexin 10
Chromosome: CHR7: 26331514 -26413949
Locus: 7p15.2
Gene Diseases
The HDAC9 SNX10 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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