HDAC9-LINGO2 Fusion FISH Probe
The HDAC9-LINGO2 Fusion FISH Probe is used to confirm a fusion of the HDAC9 and LINGO2 genes. The fusion of the HDAC9 and LINGO2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HDAC9-LINGO2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-RERE | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-REOR | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-REGO | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-REGR | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-REAQ | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-ORRE | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-OROR | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-ORGO | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-ORAQ | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-GORE | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-GOOR | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-GOGO | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-GOGR | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-GOAQ | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-GRRE | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-GROR | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-GRGO | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-GRGR | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-GRAQ | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-AQRE | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-AQOR | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-AQGO | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-AQGR | 20 (40 μL) | 200 μL |
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| HDAC9-LINGO2-20-AQAQ | 20 (40 μL) | 200 μL |
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HDAC9 Gene Summary
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Histone Deacetylase 9
Chromosome: CHR7: 18126571 -18708466
Locus: 7p21.1
LINGO2 Gene Summary
The Leucine Rich Repeat And Ig Domain Containing 2 (LINGO2) gene is located on chr9 :27948527-28719303 at 9p21.2-p21.1.
Gene Name: Leucine Rich Repeat And Ig Domain Containing 2
Chromosome: CHR9: 27948527 -28719303
Locus: 9p21.2-p21.1
Gene Diseases
The HDAC9 LINGO2 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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