HDAC9-C8ORF34 Fusion FISH Probe
The HDAC9-C8ORF34 Fusion FISH Probe is used to confirm a fusion of the HDAC9 and C8ORF34 genes. The fusion of the HDAC9 and C8ORF34 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HDAC9-C8ORF34-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-RERE | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-REOR | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-REGO | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-REGR | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-REAQ | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-ORRE | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-OROR | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-ORGO | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-ORAQ | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-GORE | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-GOOR | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-GOGO | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-GOGR | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-GOAQ | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-GRRE | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-GROR | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-GRGO | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-GRGR | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-GRAQ | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-AQRE | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-AQOR | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-AQGO | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-AQGR | 20 (40 μL) | 200 μL |
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| HDAC9-C8ORF34-20-AQAQ | 20 (40 μL) | 200 μL |
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HDAC9 Gene Summary
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Histone Deacetylase 9
Chromosome: CHR7: 18126571 -18708466
Locus: 7p21.1
C8orf34 Gene Summary
This gene encodes a protein that is related to the cyclic AMP dependent protein kinase regulators. Naturally occurring mutations in this gene are associated with an increased risk for severe toxicities, such as diarrhea and neutropenia, in patients undergoing chemotherapeutic treatment. [provided by RefSeq, Mar 2017]
Gene Name: Chromosome 8 Open Reading Frame 34
Chromosome: CHR8: 69242956 -69731258
Locus: 8q13.2
Gene Diseases
The HDAC9 C8ORF34 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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