HDAC2-TRDN Fusion FISH Probe
The HDAC2-TRDN Fusion FISH Probe is used to confirm a fusion of the HDAC2 and TRDN genes. The fusion of the HDAC2 and TRDN genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HDAC2-TRDN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-RERE | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-REOR | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-REGO | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-REGR | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-REAQ | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-ORRE | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-OROR | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-ORGO | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-ORAQ | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-GORE | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-GOOR | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-GOGO | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-GOGR | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-GOAQ | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-GRRE | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-GROR | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-GRGO | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-GRGR | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-GRAQ | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-AQRE | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-AQOR | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-AQGO | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-AQGR | 20 (40 μL) | 200 μL |
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| HDAC2-TRDN-20-AQAQ | 20 (40 μL) | 200 μL |
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HDAC2 Gene Summary
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
Gene Name: Histone Deacetylase 2
Chromosome: CHR6: 114257319 -114292359
Locus: 6q21
TRDN Gene Summary
This gene encodes an integral membrane protein that contains a single transmembrane domain. As similar protein in rabbits plays a role in skeletal muscle excitation-contraction coupling as part of the calcium release complex in association with the ryanodine receptor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and single nucleotide polymorphisms in this gene may be markers for IgA nephritis. [provided by RefSeq, Oct 2011]
Gene Name: Triadin
Chromosome: CHR6: 123537482 -123957942
Locus: 6q22.31
Gene Diseases
The HDAC2 TRDN Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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