HDAC1-LRRC42 Fusion FISH Probe
The HDAC1-LRRC42 Fusion FISH Probe is used to confirm a fusion of the HDAC1 and LRRC42 genes. The fusion of the HDAC1 and LRRC42 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HDAC1-LRRC42-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-RERE | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-REOR | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-REGO | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-REGR | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-REAQ | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-ORRE | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-OROR | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-ORGO | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-ORAQ | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-GORE | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-GOOR | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-GOGO | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-GOGR | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-GOAQ | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-GRRE | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-GROR | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-GRGO | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-GRGR | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-GRAQ | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-AQRE | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-AQOR | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-AQGO | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-AQGR | 20 (40 μL) | 200 μL |
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| HDAC1-LRRC42-20-AQAQ | 20 (40 μL) | 200 μL |
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HDAC1 Gene Summary
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
Gene Name: Histone Deacetylase 1
Chromosome: CHR1: 32757707 -32799224
Locus: 1p35.2-p35.1
LRRC42 Gene Summary
The Leucine Rich Repeat Containing 42 (LRRC42) gene is located on chr1 :54412036-54433839 at 1p32.3.
Gene Name: Leucine Rich Repeat Containing 42
Chromosome: CHR1: 54412036 -54433839
Locus: 1p32.3
Gene Diseases
The HDAC1 LRRC42 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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