HCFC2-ANKS1B Fusion FISH Probe
The HCFC2-ANKS1B Fusion FISH Probe is used to confirm a fusion of the HCFC2 and ANKS1B genes. The fusion of the HCFC2 and ANKS1B genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HCFC2-ANKS1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-RERE | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-REOR | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-REGO | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-REGR | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-REAQ | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-ORRE | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-OROR | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-ORGO | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-GORE | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-GOOR | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-GOGO | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-GOGR | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-GRRE | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-GROR | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-GRGO | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-GRGR | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-AQRE | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-AQOR | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-AQGO | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-AQGR | 20 (40 μL) | 200 μL |
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| HCFC2-ANKS1B-20-AQAQ | 20 (40 μL) | 200 μL |
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HCFC2 Gene Summary
This gene encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The original Herpes host cell factor, however, is effective at initiating viral infection while the encoded protein is not. Transcripts of varying length due to alternative polyadenylation signals have been described. [provided by RefSeq, Jul 2008]
Gene Name: Host Cell Factor C2
Chromosome: CHR12: 104458235 -104500304
Locus: 12q23.3
ANKS1B Gene Summary
This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Name: Ankyrin Repeat And Sterile Alpha Motif Domain Containing 1B
Chromosome: CHR12: 99128568 -100378432
Locus: 12q23.1
Gene Diseases
The HCFC2 ANKS1B Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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