HBS1L-IL9 Fusion FISH Probe
The HBS1L-IL9 Fusion FISH Probe is used to confirm a fusion of the HBS1L and IL9 genes. The fusion of the HBS1L and IL9 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HBS1L-IL9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-RERE | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-REOR | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-REGO | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-REGR | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-REAQ | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-ORRE | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-OROR | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-ORGO | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-ORAQ | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-GORE | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-GOOR | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-GOGO | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-GOGR | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-GOAQ | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-GRRE | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-GROR | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-GRGO | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-GRGR | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-GRAQ | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-AQRE | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-AQOR | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-AQGO | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-AQGR | 20 (40 μL) | 200 μL |
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| HBS1L-IL9-20-AQAQ | 20 (40 μL) | 200 μL |
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IL9 Gene Summary
The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 2008]
Gene Name: Interleukin 9
Chromosome: CHR5: 135227934 -135231516
Locus: 5q31.1
HBS1L Gene Summary
This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, May 2009]
Gene Name: HBS1 Like Translational GTPase
Chromosome: CHR6: 135281516 -135376036
Locus: 6q23.3
Gene Diseases
The HBS1L IL9 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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