HAUS8-CARS Fusion FISH Probe
The HAUS8-CARS Fusion FISH Probe is used to confirm a fusion of the HAUS8 and CARS genes. The fusion of the HAUS8 and CARS genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HAUS8-CARS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-RERE | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-REOR | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-REGO | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-REGR | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-REAQ | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-ORRE | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-OROR | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-ORGO | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-ORAQ | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-GORE | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-GOOR | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-GOGO | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-GOGR | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-GOAQ | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-GRRE | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-GROR | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-GRGO | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-GRGR | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-GRAQ | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-AQRE | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-AQOR | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-AQGO | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-AQGR | 20 (40 μL) | 200 μL |
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| HAUS8-CARS-20-AQAQ | 20 (40 μL) | 200 μL |
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CARS Gene Summary
This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2010]
Gene Name: Cysteinyl-tRNA Synthetase
Chromosome: CHR11: 3022151 -3078681
Locus: 11p15.4
HAUS8 Gene Summary
HAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]
Gene Name: HAUS Augmin Like Complex Subunit 8
Chromosome: CHR19: 17160570 -17186343
Locus: 19p13.11
Gene Diseases
The HAUS8 CARS Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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