HAUS6-PMPCA Fusion FISH Probe
The HAUS6-PMPCA Fusion FISH Probe is used to confirm a fusion of the HAUS6 and PMPCA genes. The fusion of the HAUS6 and PMPCA genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HAUS6-PMPCA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-RERE | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-REOR | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-REGO | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-REGR | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-REAQ | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-ORRE | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-OROR | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-ORGO | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-ORAQ | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-GORE | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-GOOR | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-GOGO | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-GOGR | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-GOAQ | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-GRRE | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-GROR | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-GRGO | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-GRGR | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-GRAQ | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-AQRE | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-AQOR | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-AQGO | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-AQGR | 20 (40 μL) | 200 μL |
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| HAUS6-PMPCA-20-AQAQ | 20 (40 μL) | 200 μL |
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PMPCA Gene Summary
The protein encoded by this gene is found in the mitochondrion, where it represents the alpha subunit of a proteolytic heterodimer. This heterodimer is responsible for cleaving the transit peptide from nuclear-encoded mitochondrial proteins. Defects in this gene are a cause of spinocerebellar ataxia, autosomal recessive 2. [provided by RefSeq, Mar 2016]
Gene Name: Peptidase, Mitochondrial Processing Alpha Subunit
Chromosome: CHR9: 139305115 -139318213
Locus: 9q34.3
HAUS6 Gene Summary
The protein encoded by this gene is a subunit of the augmin complex. The augmin complex plays a role in microtubule attachment to the kinetochore and central spindle formation. This protein may have a role in efficient chromosome congression and segregation by promoting microtubule-dependent microtubule amplification. Pseudogenes of this gene are located on chromosomes 7 and 20. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
Gene Name: HAUS Augmin Like Complex Subunit 6
Chromosome: CHR9: 19053140 -19102902
Locus: 9p22.1
Gene Diseases
The HAUS6 PMPCA Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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