HAT1-EXOC6B Fusion FISH Probe
The HAT1-EXOC6B Fusion FISH Probe is used to confirm a fusion of the HAT1 and EXOC6B genes. The fusion of the HAT1 and EXOC6B genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HAT1-EXOC6B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-RERE | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-REOR | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-REGO | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-REGR | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-REAQ | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-ORRE | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-OROR | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-ORGO | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-ORAQ | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-GORE | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-GOOR | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-GOGO | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-GOGR | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-GOAQ | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-GRRE | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-GROR | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-GRGO | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-GRGR | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-GRAQ | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-AQRE | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-AQOR | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-AQGO | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-AQGR | 20 (40 μL) | 200 μL |
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| HAT1-EXOC6B-20-AQAQ | 20 (40 μL) | 200 μL |
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HAT1 Gene Summary
The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2009]
Gene Name: Histone Acetyltransferase 1
Chromosome: CHR2: 172778934 -172848600
Locus: 2q31.1
EXOC6B Gene Summary
This gene encodes a protein which is a part of the evolutionarily conserved exocyst, a multimeric protein complex necessary for exocytosis, which in turn, is crucial for cell growth, polarity and migration. Disruption of this gene may be associated with phenotypes exhibiting multiple symptoms including intellectual disability and developmental delay (DD). [provided by RefSeq, Jun 2016]
Gene Name: Exocyst Complex Component 6B
Chromosome: CHR2: 72406443 -73053177
Locus: 2p13.2
Gene Diseases
The HAT1 EXOC6B Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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