HADH-HPGD Fusion FISH Probe
The HADH-HPGD Fusion FISH Probe is used to confirm a fusion of the HADH and HPGD genes. The fusion of the HADH and HPGD genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HADH-HPGD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-RERE | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-REOR | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-REGO | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-REGR | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-REAQ | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-ORRE | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-OROR | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-ORGO | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-ORAQ | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-GORE | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-GOOR | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-GOGO | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-GOGR | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-GOAQ | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-GRRE | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-GROR | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-GRGO | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-GRGR | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-GRAQ | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-AQRE | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-AQOR | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-AQGO | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-AQGR | 20 (40 μL) | 200 μL |
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| HADH-HPGD-20-AQAQ | 20 (40 μL) | 200 μL |
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HADH Gene Summary
This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene of this gene on chromosome 15. [provided by RefSeq, May 2010]
Gene Name: Hydroxyacyl-CoA Dehydrogenase
Chromosome: CHR4: 108910869 -108956331
Locus: 4q25
HPGD Gene Summary
This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Gene Name: 15-hydroxyprostaglandin Dehydrogenase
Chromosome: CHR4: 175411327 -175444044
Locus: 4q34.1
Gene Diseases
The HADH HPGD Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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