HACE1-FBLN1 Fusion FISH Probe
The HACE1-FBLN1 Fusion FISH Probe is used to confirm a fusion of the HACE1 and FBLN1 genes. The fusion of the HACE1 and FBLN1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HACE1-FBLN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-RERE | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-REOR | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-REGO | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-REGR | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-REAQ | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-ORRE | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-OROR | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-ORGO | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-GORE | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-GOOR | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-GOGO | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-GOGR | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-GRRE | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-GROR | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-GRGO | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-GRGR | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-AQRE | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-AQOR | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-AQGO | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-AQGR | 20 (40 μL) | 200 μL |
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| HACE1-FBLN1-20-AQAQ | 20 (40 μL) | 200 μL |
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FBLN1 Gene Summary
Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants. [provided by RefSeq, Jul 2008]
Gene Name: Fibulin 1
Chromosome: CHR22: 45898718 -45997014
Locus: 22q13.31
HACE1 Gene Summary
This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor. [provided by RefSeq, Mar 2016]
Gene Name: HECT Domain And Ankyrin Repeat Containing E3 Ubiquitin Protein Ligase 1
Chromosome: CHR6: 105175967 -105307794
Locus: 6q16.3
Gene Diseases
The HACE1 FBLN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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