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GYS1-HOMER3 Fusion FISH Probe

The GYS1-HOMER3 Fusion FISH Probe is used to confirm a fusion of the GYS1 and HOMER3 genes. The fusion of the GYS1 and HOMER3 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
GYS1-HOMER3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
GYS1-HOMER3-20-RERE 20 (40 μL) 200 μL
GYS1-HOMER3-20-REOR 20 (40 μL) 200 μL
GYS1-HOMER3-20-REGO 20 (40 μL) 200 μL
GYS1-HOMER3-20-REGR 20 (40 μL) 200 μL
GYS1-HOMER3-20-REAQ 20 (40 μL) 200 μL
GYS1-HOMER3-20-ORRE 20 (40 μL) 200 μL
GYS1-HOMER3-20-OROR 20 (40 μL) 200 μL
GYS1-HOMER3-20-ORGO 20 (40 μL) 200 μL
GYS1-HOMER3-20-ORAQ 20 (40 μL) 200 μL
GYS1-HOMER3-20-GORE 20 (40 μL) 200 μL
GYS1-HOMER3-20-GOOR 20 (40 μL) 200 μL
GYS1-HOMER3-20-GOGO 20 (40 μL) 200 μL
GYS1-HOMER3-20-GOGR 20 (40 μL) 200 μL
GYS1-HOMER3-20-GOAQ 20 (40 μL) 200 μL
GYS1-HOMER3-20-GRRE 20 (40 μL) 200 μL
GYS1-HOMER3-20-GROR 20 (40 μL) 200 μL
GYS1-HOMER3-20-GRGO 20 (40 μL) 200 μL
GYS1-HOMER3-20-GRGR 20 (40 μL) 200 μL
GYS1-HOMER3-20-GRAQ 20 (40 μL) 200 μL
GYS1-HOMER3-20-AQRE 20 (40 μL) 200 μL
GYS1-HOMER3-20-AQOR 20 (40 μL) 200 μL
GYS1-HOMER3-20-AQGO 20 (40 μL) 200 μL
GYS1-HOMER3-20-AQGR 20 (40 μL) 200 μL
GYS1-HOMER3-20-AQAQ 20 (40 μL) 200 μL

GYS1 Gene Summary

The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]

Gene Name: Glycogen Synthase 1

Chromosome: CHR19: 49471381 -49496610

Locus: 19q13.33

HOMER3 Gene Summary

This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]

Gene Name: Homer Scaffolding Protein 3

Chromosome: CHR19: 19040009 -19052041

Locus: 19p13.11

Gene Diseases

The GYS1 HOMER3 Fusion has been associated with the following diseases:

Disease Name
Ovarian Serous Cystadenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.