GXYLT2-PRICKLE2 Fusion FISH Probe
The GXYLT2-PRICKLE2 Fusion FISH Probe is used to confirm a fusion of the GXYLT2 and PRICKLE2 genes. The fusion of the GXYLT2 and PRICKLE2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GXYLT2-PRICKLE2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-RERE | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-REOR | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-REGO | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-REGR | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-REAQ | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-ORRE | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-OROR | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-ORGO | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-ORAQ | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-GORE | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-GOOR | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-GOGO | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-GOGR | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-GOAQ | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-GRRE | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-GROR | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-GRGO | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-GRGR | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-GRAQ | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-AQRE | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-AQOR | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-AQGO | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-AQGR | 20 (40 μL) | 200 μL |
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| GXYLT2-PRICKLE2-20-AQAQ | 20 (40 μL) | 200 μL |
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PRICKLE2 Gene Summary
This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated with progressive myoclonic epilepsy type 5. [provided by RefSeq, Dec 2011]
Gene Name: Prickle Planar Cell Polarity Protein 2
Chromosome: CHR3: 64079525 -64211131
Locus: 3p14.1
GXYLT2 Gene Summary
The protein encoded by this gene is a xylosyltransferase that elongates O-linked glucose bound to epidermal growth factor (EGF) repeats. The encoded protein catalyzes the addition of xylose to the O-glucose-modified residues of EGF repeats of Notch proteins. [provided by RefSeq, Sep 2016]
Gene Name: Glucoside Xylosyltransferase 2
Chromosome: CHR3: 72937384 -73024522
Locus: 3p13
Gene Diseases
The GXYLT2 PRICKLE2 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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