SEARCH OUR PRODUCT CATALOG

GUCY2C-ART4 Fusion FISH Probe

The GUCY2C-ART4 Fusion FISH Probe is used to confirm a fusion of the GUCY2C and ART4 genes. The fusion of the GUCY2C and ART4 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
GUCY2C-ART4-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
GUCY2C-ART4-20-RERE 20 (40 μL) 200 μL
GUCY2C-ART4-20-REOR 20 (40 μL) 200 μL
GUCY2C-ART4-20-REGO 20 (40 μL) 200 μL
GUCY2C-ART4-20-REGR 20 (40 μL) 200 μL
GUCY2C-ART4-20-REAQ 20 (40 μL) 200 μL
GUCY2C-ART4-20-ORRE 20 (40 μL) 200 μL
GUCY2C-ART4-20-OROR 20 (40 μL) 200 μL
GUCY2C-ART4-20-ORGO 20 (40 μL) 200 μL
GUCY2C-ART4-20-ORAQ 20 (40 μL) 200 μL
GUCY2C-ART4-20-GORE 20 (40 μL) 200 μL
GUCY2C-ART4-20-GOOR 20 (40 μL) 200 μL
GUCY2C-ART4-20-GOGO 20 (40 μL) 200 μL
GUCY2C-ART4-20-GOGR 20 (40 μL) 200 μL
GUCY2C-ART4-20-GOAQ 20 (40 μL) 200 μL
GUCY2C-ART4-20-GRRE 20 (40 μL) 200 μL
GUCY2C-ART4-20-GROR 20 (40 μL) 200 μL
GUCY2C-ART4-20-GRGO 20 (40 μL) 200 μL
GUCY2C-ART4-20-GRGR 20 (40 μL) 200 μL
GUCY2C-ART4-20-GRAQ 20 (40 μL) 200 μL
GUCY2C-ART4-20-AQRE 20 (40 μL) 200 μL
GUCY2C-ART4-20-AQOR 20 (40 μL) 200 μL
GUCY2C-ART4-20-AQGO 20 (40 μL) 200 μL
GUCY2C-ART4-20-AQGR 20 (40 μL) 200 μL
GUCY2C-ART4-20-AQAQ 20 (40 μL) 200 μL

ART4 Gene Summary

This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. Antigens of the Dombrock blood group system are located on the gene product, which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane. Allelic variants, some of which lead to adverse transfusion reactions, are known. [provided by RefSeq, Jul 2008]

Gene Name: ADP-ribosyltransferase 4 (Dombrock Blood Group)

Chromosome: CHR12: 14982244 -14996413

Locus: 12p12.3

GUCY2C Gene Summary

This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). [provided by RefSeq, Nov 2016]

Gene Name: Guanylate Cyclase 2C

Chromosome: CHR12: 14765567 -14849519

Locus: 12p12.3

Gene Diseases

The GUCY2C ART4 Fusion has been associated with the following diseases:

Disease Name
Stomach Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.