GTPBP2-HIST1H2BJ Fusion FISH Probe
The GTPBP2-HIST1H2BJ Fusion FISH Probe is used to confirm a fusion of the GTPBP2 and HIST1H2BJ genes. The fusion of the GTPBP2 and HIST1H2BJ genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GTPBP2-HIST1H2BJ-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-RERE | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-REOR | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-REGO | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-REGR | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-REAQ | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-ORRE | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-OROR | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-ORGO | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-ORAQ | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-GORE | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-GOOR | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-GOGO | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-GOGR | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-GOAQ | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-GRRE | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-GROR | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-GRGO | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-GRGR | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-GRAQ | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-AQRE | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-AQOR | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-AQGO | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-AQGR | 20 (40 μL) | 200 μL |
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| GTPBP2-HIST1H2BJ-20-AQAQ | 20 (40 μL) | 200 μL |
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HIST1H2BJ Gene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015]
Gene Name: Histone Cluster 1 H2B Family Member J
Chromosome: CHR6: 27100094 -27100575
Locus: 6p22.1
GTPBP2 Gene Summary
GTP-binding proteins, or G proteins, constitute a superfamily capable of binding GTP or GDP. G proteins are activated by binding GTP and are inactivated by hydrolyzing GTP to GDP. This general mechanism enables G proteins to perform a wide range of biologic activities.[supplied by OMIM, Jan 2003]
Gene Name: GTP Binding Protein 2
Chromosome: CHR6: 43588217 -43596936
Locus: 6p21.1
Gene Diseases
The GTPBP2 HIST1H2BJ Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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