GTF2IRD1-ZAN Fusion FISH Probe
The GTF2IRD1-ZAN Fusion FISH Probe is used to confirm a fusion of the GTF2IRD1 and ZAN genes. The fusion of the GTF2IRD1 and ZAN genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GTF2IRD1-ZAN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-RERE | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-REOR | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-REGO | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-REGR | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-REAQ | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-ORRE | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-OROR | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-ORGO | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-ORAQ | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-GORE | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-GOOR | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-GOGO | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-GOGR | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-GOAQ | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-GRRE | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-GROR | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-GRGO | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-GRGR | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-GRAQ | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-AQRE | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-AQOR | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-AQGO | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-AQGR | 20 (40 μL) | 200 μL |
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| GTF2IRD1-ZAN-20-AQAQ | 20 (40 μL) | 200 μL |
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ZAN Gene Summary
This gene encodes a protein that functions in the species specificity of sperm adhesion to the egg zona pellucida. The encoded protein is located in the acrosome and may be involved in signaling or gamete recognition. An allelic polymorphism in this gene results in both functional and frameshifted alleles; the reference genome represents the functional allele. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Gene Name: Zonadhesin (gene/pseudogene)
Chromosome: CHR7: 100331248 -100395419
Locus: 7q22.1
GTF2IRD1 Gene Summary
The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
Gene Name: GTF2I Repeat Domain Containing 1
Chromosome: CHR7: 73868119 -74016920
Locus: 7q11.23
Gene Diseases
The GTF2IRD1 ZAN Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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