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GTF2E2-GSR Fusion FISH Probe

The GTF2E2-GSR Fusion FISH Probe is used to confirm a fusion of the GTF2E2 and GSR genes. The fusion of the GTF2E2 and GSR genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
GTF2E2-GSR-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
GTF2E2-GSR-20-RERE 20 (40 μL) 200 μL
GTF2E2-GSR-20-REOR 20 (40 μL) 200 μL
GTF2E2-GSR-20-REGO 20 (40 μL) 200 μL
GTF2E2-GSR-20-REGR 20 (40 μL) 200 μL
GTF2E2-GSR-20-REAQ 20 (40 μL) 200 μL
GTF2E2-GSR-20-ORRE 20 (40 μL) 200 μL
GTF2E2-GSR-20-OROR 20 (40 μL) 200 μL
GTF2E2-GSR-20-ORGO 20 (40 μL) 200 μL
GTF2E2-GSR-20-ORAQ 20 (40 μL) 200 μL
GTF2E2-GSR-20-GORE 20 (40 μL) 200 μL
GTF2E2-GSR-20-GOOR 20 (40 μL) 200 μL
GTF2E2-GSR-20-GOGO 20 (40 μL) 200 μL
GTF2E2-GSR-20-GOGR 20 (40 μL) 200 μL
GTF2E2-GSR-20-GOAQ 20 (40 μL) 200 μL
GTF2E2-GSR-20-GRRE 20 (40 μL) 200 μL
GTF2E2-GSR-20-GROR 20 (40 μL) 200 μL
GTF2E2-GSR-20-GRGO 20 (40 μL) 200 μL
GTF2E2-GSR-20-GRGR 20 (40 μL) 200 μL
GTF2E2-GSR-20-GRAQ 20 (40 μL) 200 μL
GTF2E2-GSR-20-AQRE 20 (40 μL) 200 μL
GTF2E2-GSR-20-AQOR 20 (40 μL) 200 μL
GTF2E2-GSR-20-AQGO 20 (40 μL) 200 μL
GTF2E2-GSR-20-AQGR 20 (40 μL) 200 μL
GTF2E2-GSR-20-AQAQ 20 (40 μL) 200 μL

GSR Gene Summary

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010]

Gene Name: Glutathione-disulfide Reductase

Chromosome: CHR8: 30535579 -30585486

Locus: 8p12

GTF2E2 Gene Summary

The general transcription factor IIE (TFIIE) is part of the RNA polymerase II transcription initiation complex, recruiting TFIIH and being essential for promoter clearance by RNA polymerase II. TFIIE is a heterodimer (and sometimes heterotetramer) of alpha and beta subunits. The protein encoded by this gene represents the beta subunit of TFIIE. [provided by RefSeq, Jan 2017]

Gene Name: General Transcription Factor IIE Subunit 2

Chromosome: CHR8: 30436030 -30515738

Locus: 8p12

Gene Diseases

The GTF2E2 GSR Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.