GTF2E2-GSR Fusion FISH Probe
The GTF2E2-GSR Fusion FISH Probe is used to confirm a fusion of the GTF2E2 and GSR genes. The fusion of the GTF2E2 and GSR genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GTF2E2-GSR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-RERE | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-REOR | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-REGO | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-REGR | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-REAQ | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-ORRE | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-OROR | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-ORGO | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-ORAQ | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-GORE | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-GOOR | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-GOGO | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-GOGR | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-GOAQ | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-GRRE | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-GROR | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-GRGO | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-GRGR | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-GRAQ | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-AQRE | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-AQOR | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-AQGO | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-AQGR | 20 (40 μL) | 200 μL |
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| GTF2E2-GSR-20-AQAQ | 20 (40 μL) | 200 μL |
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GSR Gene Summary
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010]
Gene Name: Glutathione-disulfide Reductase
Chromosome: CHR8: 30535579 -30585486
Locus: 8p12
GTF2E2 Gene Summary
The general transcription factor IIE (TFIIE) is part of the RNA polymerase II transcription initiation complex, recruiting TFIIH and being essential for promoter clearance by RNA polymerase II. TFIIE is a heterodimer (and sometimes heterotetramer) of alpha and beta subunits. The protein encoded by this gene represents the beta subunit of TFIIE. [provided by RefSeq, Jan 2017]
Gene Name: General Transcription Factor IIE Subunit 2
Chromosome: CHR8: 30436030 -30515738
Locus: 8p12
Gene Diseases
The GTF2E2 GSR Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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