GTF2E2-FBXO16 Fusion FISH Probe
The GTF2E2-FBXO16 Fusion FISH Probe is used to confirm a fusion of the GTF2E2 and FBXO16 genes. The fusion of the GTF2E2 and FBXO16 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GTF2E2-FBXO16-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-RERE | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-REOR | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-REGO | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-REGR | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-REAQ | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-ORRE | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-OROR | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-ORGO | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-ORAQ | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-GORE | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-GOOR | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-GOGO | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-GOGR | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-GOAQ | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-GRRE | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-GROR | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-GRGO | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-GRGR | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-GRAQ | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-AQRE | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-AQOR | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-AQGO | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-AQGR | 20 (40 μL) | 200 μL |
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| GTF2E2-FBXO16-20-AQAQ | 20 (40 μL) | 200 μL |
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GTF2E2 Gene Summary
The general transcription factor IIE (TFIIE) is part of the RNA polymerase II transcription initiation complex, recruiting TFIIH and being essential for promoter clearance by RNA polymerase II. TFIIE is a heterodimer (and sometimes heterotetramer) of alpha and beta subunits. The protein encoded by this gene represents the beta subunit of TFIIE. [provided by RefSeq, Jan 2017]
Gene Name: General Transcription Factor IIE Subunit 2
Chromosome: CHR8: 30436030 -30515738
Locus: 8p12
FBXO16 Gene Summary
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Name: F-box Protein 16
Chromosome: CHR8: 28285928 -28347784
Locus: 8p21.1
Gene Diseases
The GTF2E2 FBXO16 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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