GTF2E2-EIF4EBP1 Fusion FISH Probe
The GTF2E2-EIF4EBP1 Fusion FISH Probe is used to confirm a fusion of the GTF2E2 and EIF4EBP1 genes. The fusion of the GTF2E2 and EIF4EBP1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GTF2E2-EIF4EBP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-RERE | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-REOR | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-REGO | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-REGR | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-REAQ | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-ORRE | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-OROR | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-ORGO | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-GORE | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-GOOR | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-GOGO | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-GOGR | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-GRRE | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-GROR | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-GRGO | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-GRGR | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-AQRE | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-AQOR | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-AQGO | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-AQGR | 20 (40 μL) | 200 μL |
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| GTF2E2-EIF4EBP1-20-AQAQ | 20 (40 μL) | 200 μL |
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EIF4EBP1 Gene Summary
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008]
Gene Name: Eukaryotic Translation Initiation Factor 4E Binding Protein 1
Chromosome: CHR8: 37888019 -37917883
Locus: 8p11.23
GTF2E2 Gene Summary
The general transcription factor IIE (TFIIE) is part of the RNA polymerase II transcription initiation complex, recruiting TFIIH and being essential for promoter clearance by RNA polymerase II. TFIIE is a heterodimer (and sometimes heterotetramer) of alpha and beta subunits. The protein encoded by this gene represents the beta subunit of TFIIE. [provided by RefSeq, Jan 2017]
Gene Name: General Transcription Factor IIE Subunit 2
Chromosome: CHR8: 30436030 -30515738
Locus: 8p12
Gene Diseases
The GTF2E2 EIF4EBP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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