GSTP1-ELP4 Fusion FISH Probe
The GSTP1-ELP4 Fusion FISH Probe is used to confirm a fusion of the GSTP1 and ELP4 genes. The fusion of the GSTP1 and ELP4 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GSTP1-ELP4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-RERE | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-REOR | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-REGO | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-REGR | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-REAQ | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-ORRE | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-OROR | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-ORGO | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-ORAQ | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-GORE | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-GOOR | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-GOGO | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-GOGR | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-GOAQ | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-GRRE | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-GROR | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-GRGO | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-GRGR | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-GRAQ | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-AQRE | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-AQOR | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-AQGO | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-AQGR | 20 (40 μL) | 200 μL |
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| GSTP1-ELP4-20-AQAQ | 20 (40 μL) | 200 μL |
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GSTP1 Gene Summary
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008]
Gene Name: Glutathione S-transferase Pi 1
Chromosome: CHR11: 67351065 -67354124
Locus: 11q13.2
ELP4 Gene Summary
This gene encodes a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation. The human gene can partially complement sensitivity phenotypes of yeast ELP4 deletion mutants. This gene has also been associated with Rolandic epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Gene Name: Elongator Acetyltransferase Complex Subunit 4
Chromosome: CHR11: 31531296 -31805329
Locus: 11p13
Gene Diseases
The GSTP1 ELP4 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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