GSTP1-ATP5G3 Fusion FISH Probe
The GSTP1-ATP5G3 Fusion FISH Probe is used to confirm a fusion of the GSTP1 and ATP5G3 genes. The fusion of the GSTP1 and ATP5G3 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GSTP1-ATP5G3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-RERE | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-REOR | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-REGO | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-REGR | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-REAQ | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-ORRE | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-OROR | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-ORGO | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-ORAQ | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-GORE | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-GOOR | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-GOGO | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-GOGR | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-GOAQ | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-GRRE | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-GROR | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-GRGO | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-GRGR | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-GRAQ | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-AQRE | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-AQOR | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-AQGO | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-AQGR | 20 (40 μL) | 200 μL |
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| GSTP1-ATP5G3-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP5G3 Gene Summary
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding different proteins have been identified. [provided by RefSeq, Jun 2010]
Gene Name: ATP Synthase, H+ Transporting, Mitochondrial Fo Complex Subunit C3 (subunit 9)
Chromosome: CHR2: 176040985 -176046490
Locus: 2q31.1
GSTP1 Gene Summary
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008]
Gene Name: Glutathione S-transferase Pi 1
Chromosome: CHR11: 67351065 -67354124
Locus: 11q13.2
Gene Diseases
The GSTP1 ATP5G3 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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