GSTP1-ARFGEF2 Fusion FISH Probe
The GSTP1-ARFGEF2 Fusion FISH Probe is used to confirm a fusion of the GSTP1 and ARFGEF2 genes. The fusion of the GSTP1 and ARFGEF2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GSTP1-ARFGEF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-RERE | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-REOR | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-REGO | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-REGR | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-REAQ | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-ORRE | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-OROR | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-ORGO | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-GORE | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-GOOR | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-GOGO | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-GOGR | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-GRRE | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-GROR | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-GRGO | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-GRGR | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-AQRE | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-AQOR | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-AQGO | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-AQGR | 20 (40 μL) | 200 μL |
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| GSTP1-ARFGEF2-20-AQAQ | 20 (40 μL) | 200 μL |
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GSTP1 Gene Summary
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008]
Gene Name: Glutathione S-transferase Pi 1
Chromosome: CHR11: 67351065 -67354124
Locus: 11q13.2
ARFGEF2 Gene Summary
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
Gene Name: ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 2
Chromosome: CHR20: 47538274 -47653230
Locus: 20q13.13
Gene Diseases
The GSTP1 ARFGEF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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