GSS-ACSS2 Fusion FISH Probe
The GSS-ACSS2 Fusion FISH Probe is used to confirm a fusion of the GSS and ACSS2 genes. The fusion of the GSS and ACSS2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GSS-ACSS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-RERE | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-REOR | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-REGO | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-REGR | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-REAQ | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-ORRE | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-OROR | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-ORGO | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-GORE | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-GOOR | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-GOGO | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-GOGR | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-GRRE | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-GROR | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-GRGO | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-GRGR | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-AQRE | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-AQOR | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-AQGO | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-AQGR | 20 (40 μL) | 200 μL |
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| GSS-ACSS2-20-AQAQ | 20 (40 μL) | 200 μL |
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GSS Gene Summary
Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency. [provided by RefSeq, Jul 2008]
Gene Name: Glutathione Synthetase
Chromosome: CHR20: 33516235 -33543601
Locus: 20q11.22
ACSS2 Gene Summary
This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
Gene Name: Acyl-CoA Synthetase Short Chain Family Member 2
Chromosome: CHR20: 33462765 -33515769
Locus: 20q11.22
Gene Diseases
The GSS ACSS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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