GSN-UVRAG Fusion FISH Probe
The GSN-UVRAG Fusion FISH Probe is used to confirm a fusion of the GSN and UVRAG genes. The fusion of the GSN and UVRAG genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GSN-UVRAG-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-RERE | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-REOR | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-REGO | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-REGR | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-REAQ | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-ORRE | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-OROR | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-ORGO | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-ORAQ | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-GORE | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-GOOR | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-GOGO | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-GOGR | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-GOAQ | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-GRRE | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-GROR | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-GRGO | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-GRGR | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-GRAQ | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-AQRE | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-AQOR | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-AQGO | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-AQGR | 20 (40 μL) | 200 μL |
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| GSN-UVRAG-20-AQAQ | 20 (40 μL) | 200 μL |
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GSN Gene Summary
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Gelsolin
Chromosome: CHR9: 124030379 -124095120
Locus: 9q33.2
UVRAG Gene Summary
This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008]
Gene Name: UV Radiation Resistance Associated
Chromosome: CHR11: 75526211 -75855282
Locus: 11q13.5
Gene Diseases
The GSN UVRAG Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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