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GSN-UTRN Fusion FISH Probe

The GSN-UTRN Fusion FISH Probe is used to confirm a fusion of the GSN and UTRN genes. The fusion of the GSN and UTRN genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
GSN-UTRN-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
GSN-UTRN-20-RERE 20 (40 μL) 200 μL
GSN-UTRN-20-REOR 20 (40 μL) 200 μL
GSN-UTRN-20-REGO 20 (40 μL) 200 μL
GSN-UTRN-20-REGR 20 (40 μL) 200 μL
GSN-UTRN-20-REAQ 20 (40 μL) 200 μL
GSN-UTRN-20-ORRE 20 (40 μL) 200 μL
GSN-UTRN-20-OROR 20 (40 μL) 200 μL
GSN-UTRN-20-ORGO 20 (40 μL) 200 μL
GSN-UTRN-20-ORAQ 20 (40 μL) 200 μL
GSN-UTRN-20-GORE 20 (40 μL) 200 μL
GSN-UTRN-20-GOOR 20 (40 μL) 200 μL
GSN-UTRN-20-GOGO 20 (40 μL) 200 μL
GSN-UTRN-20-GOGR 20 (40 μL) 200 μL
GSN-UTRN-20-GOAQ 20 (40 μL) 200 μL
GSN-UTRN-20-GRRE 20 (40 μL) 200 μL
GSN-UTRN-20-GROR 20 (40 μL) 200 μL
GSN-UTRN-20-GRGO 20 (40 μL) 200 μL
GSN-UTRN-20-GRGR 20 (40 μL) 200 μL
GSN-UTRN-20-GRAQ 20 (40 μL) 200 μL
GSN-UTRN-20-AQRE 20 (40 μL) 200 μL
GSN-UTRN-20-AQOR 20 (40 μL) 200 μL
GSN-UTRN-20-AQGO 20 (40 μL) 200 μL
GSN-UTRN-20-AQGR 20 (40 μL) 200 μL
GSN-UTRN-20-AQAQ 20 (40 μL) 200 μL

GSN Gene Summary

The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: Gelsolin

Chromosome: CHR9: 124030379 -124095120

Locus: 9q33.2

UTRN Gene Summary

This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]

Gene Name: Utrophin

Chromosome: CHR6: 144612872 -145174170

Locus: 6q24.2

Gene Diseases

The GSN UTRN Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.