GSN-UTRN Fusion FISH Probe
The GSN-UTRN Fusion FISH Probe is used to confirm a fusion of the GSN and UTRN genes. The fusion of the GSN and UTRN genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GSN-UTRN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-RERE | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-REOR | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-REGO | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-REGR | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-REAQ | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-ORRE | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-OROR | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-ORGO | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-ORAQ | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-GORE | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-GOOR | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-GOGO | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-GOGR | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-GOAQ | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-GRRE | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-GROR | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-GRGO | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-GRGR | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-GRAQ | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-AQRE | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-AQOR | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-AQGO | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-AQGR | 20 (40 μL) | 200 μL |
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| GSN-UTRN-20-AQAQ | 20 (40 μL) | 200 μL |
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GSN Gene Summary
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Gelsolin
Chromosome: CHR9: 124030379 -124095120
Locus: 9q33.2
UTRN Gene Summary
This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
Gene Name: Utrophin
Chromosome: CHR6: 144612872 -145174170
Locus: 6q24.2
Gene Diseases
The GSN UTRN Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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