GSK3B-WNK2 Fusion FISH Probe
The GSK3B-WNK2 Fusion FISH Probe is used to confirm a fusion of the GSK3B and WNK2 genes. The fusion of the GSK3B and WNK2 genes has been associated with Pheochromocytoma And Paraganglioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GSK3B-WNK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-RERE | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-REOR | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-REGO | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-REGR | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-REAQ | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-ORRE | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-OROR | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-ORGO | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-GORE | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-GOOR | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-GOGO | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-GOGR | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-GRRE | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-GROR | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-GRGO | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-GRGR | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-AQRE | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-AQOR | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-AQGO | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-AQGR | 20 (40 μL) | 200 μL |
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| GSK3B-WNK2-20-AQAQ | 20 (40 μL) | 200 μL |
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GSK3B Gene Summary
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017]
Gene Name: Glycogen Synthase Kinase 3 Beta
Chromosome: CHR3: 119540801 -119813264
Locus: 3q13.33
WNK2 Gene Summary
The protein encoded by this gene is a cytoplasmic serine-threonine kinase that belongs to the protein kinase superfamily. The protein plays an important role in the regulation of electrolyte homeostasis, cell signaling survival, and proliferation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Name: WNK Lysine Deficient Protein Kinase 2
Chromosome: CHR9: 95947211 -96082854
Locus: 9q22.31
Gene Diseases
The GSK3B WNK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Pheochromocytoma And Paraganglioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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