GSK3B-LSAMP Fusion FISH Probe
The GSK3B-LSAMP Fusion FISH Probe is used to confirm a fusion of the GSK3B and LSAMP genes. The fusion of the GSK3B and LSAMP genes has been associated with Breast Invasive Carcinoma, and Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GSK3B-LSAMP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-RERE | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-REOR | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-REGO | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-REGR | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-REAQ | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-ORRE | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-OROR | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-ORGO | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-ORAQ | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-GORE | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-GOOR | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-GOGO | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-GOGR | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-GOAQ | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-GRRE | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-GROR | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-GRGO | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-GRGR | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-GRAQ | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-AQRE | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-AQOR | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-AQGO | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-AQGR | 20 (40 μL) | 200 μL |
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| GSK3B-LSAMP-20-AQAQ | 20 (40 μL) | 200 μL |
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GSK3B Gene Summary
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017]
Gene Name: Glycogen Synthase Kinase 3 Beta
Chromosome: CHR3: 119540801 -119813264
Locus: 3q13.33
LSAMP Gene Summary
This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system. The encoded protein may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
Gene Name: Limbic System-associated Membrane Protein
Chromosome: CHR3: 115521209 -116164385
Locus: 3q13.31
Gene Diseases
The GSK3B LSAMP Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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