GSK3B-ATP11B Fusion FISH Probe
The GSK3B-ATP11B Fusion FISH Probe is used to confirm a fusion of the GSK3B and ATP11B genes. The fusion of the GSK3B and ATP11B genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GSK3B-ATP11B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-RERE | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-REOR | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-REGO | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-REGR | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-REAQ | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-ORRE | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-OROR | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-ORGO | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-ORAQ | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-GORE | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-GOOR | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-GOGO | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-GOGR | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-GOAQ | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-GRRE | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-GROR | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-GRGO | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-GRGR | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-GRAQ | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-AQRE | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-AQOR | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-AQGO | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-AQGR | 20 (40 μL) | 200 μL |
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| GSK3B-ATP11B-20-AQAQ | 20 (40 μL) | 200 μL |
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GSK3B Gene Summary
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017]
Gene Name: Glycogen Synthase Kinase 3 Beta
Chromosome: CHR3: 119540801 -119813264
Locus: 3q13.33
ATP11B Gene Summary
P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[supplied by OMIM, Feb 2005]
Gene Name: ATPase Phospholipid Transporting 11B (putative)
Chromosome: CHR3: 182511290 -182639421
Locus: 3q26.33
Gene Diseases
The GSK3B ATP11B Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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