GRK5-SUMF1 Fusion FISH Probe
The GRK5-SUMF1 Fusion FISH Probe is used to confirm a fusion of the GRK5 and SUMF1 genes. The fusion of the GRK5 and SUMF1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GRK5-SUMF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-RERE | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-REOR | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-REGO | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-REGR | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-REAQ | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-ORRE | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-OROR | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-ORGO | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-GORE | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-GOOR | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-GOGO | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-GOGR | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-GRRE | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-GROR | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-GRGO | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-GRGR | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-AQRE | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-AQOR | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-AQGO | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-AQGR | 20 (40 μL) | 200 μL |
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| GRK5-SUMF1-20-AQAQ | 20 (40 μL) | 200 μL |
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GRK5 Gene Summary
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). [provided by RefSeq, Jul 2008]
Gene Name: G Protein-coupled Receptor Kinase 5
Chromosome: CHR10: 120967196 -121215131
Locus: 10q26.11
SUMF1 Gene Summary
This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Gene Name: Sulfatase Modifying Factor 1
Chromosome: CHR3: 4402828 -4508966
Locus: 3p26.1
Gene Diseases
The GRK5 SUMF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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