GRK5-PDZD8 Fusion FISH Probe
The GRK5-PDZD8 Fusion FISH Probe is used to confirm a fusion of the GRK5 and PDZD8 genes. The fusion of the GRK5 and PDZD8 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GRK5-PDZD8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-RERE | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-REOR | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-REGO | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-REGR | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-REAQ | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-ORRE | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-OROR | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-ORGO | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-ORAQ | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-GORE | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-GOOR | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-GOGO | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-GOGR | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-GOAQ | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-GRRE | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-GROR | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-GRGO | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-GRGR | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-GRAQ | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-AQRE | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-AQOR | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-AQGO | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-AQGR | 20 (40 μL) | 200 μL |
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| GRK5-PDZD8-20-AQAQ | 20 (40 μL) | 200 μL |
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GRK5 Gene Summary
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). [provided by RefSeq, Jul 2008]
Gene Name: G Protein-coupled Receptor Kinase 5
Chromosome: CHR10: 120967196 -121215131
Locus: 10q26.11
PDZD8 Gene Summary
The PDZ Domain Containing 8 (PDZD8) gene is located on chr10 :119042605-119134937 at 10q25.3-q26.11.
Gene Name: PDZ Domain Containing 8
Chromosome: CHR10: 119042605 -119134937
Locus: 10q25.3-q26.11
Gene Diseases
The GRK5 PDZD8 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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