GRIP1-NR2E3 Fusion FISH Probe
The GRIP1-NR2E3 Fusion FISH Probe is used to confirm a fusion of the GRIP1 and NR2E3 genes. The fusion of the GRIP1 and NR2E3 genes has been associated with Pheochromocytoma And Paraganglioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GRIP1-NR2E3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-RERE | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-REOR | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-REGO | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-REGR | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-REAQ | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-ORRE | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-OROR | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-ORGO | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-ORAQ | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-GORE | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-GOOR | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-GOGO | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-GOGR | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-GOAQ | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-GRRE | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-GROR | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-GRGO | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-GRGR | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-GRAQ | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-AQRE | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-AQOR | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-AQGO | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-AQGR | 20 (40 μL) | 200 μL |
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| GRIP1-NR2E3-20-AQAQ | 20 (40 μL) | 200 μL |
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NR2E3 Gene Summary
This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Nuclear Receptor Subfamily 2 Group E Member 3
Chromosome: CHR15: 72102893 -72110597
Locus: 15q23
GRIP1 Gene Summary
This gene encodes a member of the glutamate receptor interacting protein family. The encoded scaffold protein binds to and mediates the trafficking and membrane organization of a number of transmembrane proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, May 2010]
Gene Name: Glutamate Receptor Interacting Protein 1
Chromosome: CHR12: 66741210 -67072925
Locus: 12q14.3
Gene Diseases
The GRIP1 NR2E3 Fusion has been associated with the following diseases:
| Disease Name |
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| Pheochromocytoma And Paraganglioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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