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GRIK4-TMPRSS4 Fusion FISH Probe

The GRIK4-TMPRSS4 Fusion FISH Probe is used to confirm a fusion of the GRIK4 and TMPRSS4 genes. The fusion of the GRIK4 and TMPRSS4 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
GRIK4-TMPRSS4-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-RERE 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-REOR 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-REGO 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-REGR 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-REAQ 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-ORRE 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-OROR 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-ORGO 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-ORAQ 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-GORE 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-GOOR 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-GOGO 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-GOGR 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-GOAQ 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-GRRE 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-GROR 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-GRGO 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-GRGR 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-GRAQ 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-AQRE 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-AQOR 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-AQGO 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-AQGR 20 (40 μL) 200 μL
GRIK4-TMPRSS4-20-AQAQ 20 (40 μL) 200 μL

GRIK4 Gene Summary

This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Gene Name: Glutamate Ionotropic Receptor Kainate Type Subunit 4

Chromosome: CHR11: 120531027 -120856969

Locus: 11q23.3

TMPRSS4 Gene Summary

This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: Transmembrane Protease, Serine 4

Chromosome: CHR11: 117947726 -117990556

Locus: 11q23.3

Gene Diseases

The GRIK4 TMPRSS4 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.