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GRIK2-WASF1 Fusion FISH Probe

The GRIK2-WASF1 Fusion FISH Probe is used to confirm a fusion of the GRIK2 and WASF1 genes. The fusion of the GRIK2 and WASF1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
GRIK2-WASF1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
GRIK2-WASF1-20-RERE 20 (40 μL) 200 μL
GRIK2-WASF1-20-REOR 20 (40 μL) 200 μL
GRIK2-WASF1-20-REGO 20 (40 μL) 200 μL
GRIK2-WASF1-20-REGR 20 (40 μL) 200 μL
GRIK2-WASF1-20-REAQ 20 (40 μL) 200 μL
GRIK2-WASF1-20-ORRE 20 (40 μL) 200 μL
GRIK2-WASF1-20-OROR 20 (40 μL) 200 μL
GRIK2-WASF1-20-ORGO 20 (40 μL) 200 μL
GRIK2-WASF1-20-ORAQ 20 (40 μL) 200 μL
GRIK2-WASF1-20-GORE 20 (40 μL) 200 μL
GRIK2-WASF1-20-GOOR 20 (40 μL) 200 μL
GRIK2-WASF1-20-GOGO 20 (40 μL) 200 μL
GRIK2-WASF1-20-GOGR 20 (40 μL) 200 μL
GRIK2-WASF1-20-GOAQ 20 (40 μL) 200 μL
GRIK2-WASF1-20-GRRE 20 (40 μL) 200 μL
GRIK2-WASF1-20-GROR 20 (40 μL) 200 μL
GRIK2-WASF1-20-GRGO 20 (40 μL) 200 μL
GRIK2-WASF1-20-GRGR 20 (40 μL) 200 μL
GRIK2-WASF1-20-GRAQ 20 (40 μL) 200 μL
GRIK2-WASF1-20-AQRE 20 (40 μL) 200 μL
GRIK2-WASF1-20-AQOR 20 (40 μL) 200 μL
GRIK2-WASF1-20-AQGO 20 (40 μL) 200 μL
GRIK2-WASF1-20-AQGR 20 (40 μL) 200 μL
GRIK2-WASF1-20-AQAQ 20 (40 μL) 200 μL

GRIK2 Gene Summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive cognitive disability. [provided by RefSeq, Jul 2008]

Gene Name: Glutamate Ionotropic Receptor Kainate Type Subunit 2

Chromosome: CHR6: 101846860 -102517958

Locus: 6q16.3

WASF1 Gene Summary

The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: WAS Protein Family Member 1

Chromosome: CHR6: 110421021 -110501207

Locus: 6q21

Gene Diseases

The GRIK2 WASF1 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.