GRIK2-GPC1 Fusion FISH Probe
The GRIK2-GPC1 Fusion FISH Probe is used to confirm a fusion of the GRIK2 and GPC1 genes. The fusion of the GRIK2 and GPC1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GRIK2-GPC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-RERE | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-REOR | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-REGO | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-REGR | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-REAQ | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-ORRE | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-OROR | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-ORGO | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-GORE | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-GOOR | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-GOGO | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-GOGR | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-GRRE | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-GROR | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-GRGO | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-GRGR | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-AQRE | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-AQOR | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-AQGO | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-AQGR | 20 (40 μL) | 200 μL |
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| GRIK2-GPC1-20-AQAQ | 20 (40 μL) | 200 μL |
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GPC1 Gene Summary
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq, Jul 2008]
Gene Name: Glypican 1
Chromosome: CHR2: 241375114 -241407495
Locus: 2q37.3
GRIK2 Gene Summary
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive cognitive disability. [provided by RefSeq, Jul 2008]
Gene Name: Glutamate Ionotropic Receptor Kainate Type Subunit 2
Chromosome: CHR6: 101846860 -102517958
Locus: 6q16.3
Gene Diseases
The GRIK2 GPC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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