GRIK2-EYS Fusion FISH Probe
The GRIK2-EYS Fusion FISH Probe is used to confirm a fusion of the GRIK2 and EYS genes. The fusion of the GRIK2 and EYS genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GRIK2-EYS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-RERE | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-REOR | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-REGO | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-REGR | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-REAQ | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-ORRE | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-OROR | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-ORGO | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-ORAQ | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-GORE | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-GOOR | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-GOGO | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-GOGR | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-GOAQ | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-GRRE | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-GROR | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-GRGO | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-GRGR | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-GRAQ | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-AQRE | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-AQOR | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-AQGO | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-AQGR | 20 (40 μL) | 200 μL |
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| GRIK2-EYS-20-AQAQ | 20 (40 μL) | 200 μL |
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GRIK2 Gene Summary
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive cognitive disability. [provided by RefSeq, Jul 2008]
Gene Name: Glutamate Ionotropic Receptor Kainate Type Subunit 2
Chromosome: CHR6: 101846860 -102517958
Locus: 6q16.3
EYS Gene Summary
The product of this gene contains multiple epidermal growth factor (EGF)-like and LamG domains. The protein is expressed in the photoreceptor layer of the retina, and the gene is mutated in autosomal recessive retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Gene Name: Eyes Shut Homolog (Drosophila)
Chromosome: CHR6: 64429875 -66417118
Locus: 6q12
Gene Diseases
The GRIK2 EYS Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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