GRID1-CXCL12 Fusion FISH Probe
The GRID1-CXCL12 Fusion FISH Probe is used to confirm a fusion of the GRID1 and CXCL12 genes. The fusion of the GRID1 and CXCL12 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GRID1-CXCL12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-RERE | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-REOR | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-REGO | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-REGR | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-REAQ | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-ORRE | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-OROR | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-ORGO | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-ORAQ | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-GORE | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-GOOR | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-GOGO | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-GOGR | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-GOAQ | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-GRRE | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-GROR | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-GRGO | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-GRGR | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-GRAQ | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-AQRE | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-AQOR | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-AQGO | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-AQGR | 20 (40 μL) | 200 μL |
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| GRID1-CXCL12-20-AQAQ | 20 (40 μL) | 200 μL |
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GRID1 Gene Summary
This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.[provided by RefSeq, Jan 2009]
Gene Name: Glutamate Ionotropic Receptor Delta Type Subunit 1
Chromosome: CHR10: 87359311 -88126250
Locus: 10q23.1-q23.2
CXCL12 Gene Summary
This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
Gene Name: C-X-C Motif Chemokine Ligand 12
Chromosome: CHR10: 44865604 -44880545
Locus: 10q11.21
Gene Diseases
The GRID1 CXCL12 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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