GRB7-KRT27 Fusion FISH Probe
The GRB7-KRT27 Fusion FISH Probe is used to confirm a fusion of the GRB7 and KRT27 genes. The fusion of the GRB7 and KRT27 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GRB7-KRT27-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-RERE | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-REOR | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-REGO | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-REGR | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-REAQ | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-ORRE | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-OROR | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-ORGO | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-ORAQ | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-GORE | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-GOOR | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-GOGO | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-GOGR | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-GOAQ | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-GRRE | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-GROR | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-GRGO | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-GRGR | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-GRAQ | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-AQRE | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-AQOR | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-AQGO | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-AQGR | 20 (40 μL) | 200 μL |
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| GRB7-KRT27-20-AQAQ | 20 (40 μL) | 200 μL |
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GRB7 Gene Summary
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Gene Name: Growth Factor Receptor Bound Protein 7
Chromosome: CHR17: 37894161 -37903538
Locus: 17q12
KRT27 Gene Summary
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]
Gene Name: Keratin 27
Chromosome: CHR17: 38933059 -38938786
Locus: 17q21.2
Gene Diseases
The GRB7 KRT27 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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