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GRB10-SCMH1 Fusion FISH Probe

The GRB10-SCMH1 Fusion FISH Probe is used to confirm a fusion of the GRB10 and SCMH1 genes. The fusion of the GRB10 and SCMH1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
GRB10-SCMH1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
GRB10-SCMH1-20-RERE 20 (40 μL) 200 μL
GRB10-SCMH1-20-REOR 20 (40 μL) 200 μL
GRB10-SCMH1-20-REGO 20 (40 μL) 200 μL
GRB10-SCMH1-20-REGR 20 (40 μL) 200 μL
GRB10-SCMH1-20-REAQ 20 (40 μL) 200 μL
GRB10-SCMH1-20-ORRE 20 (40 μL) 200 μL
GRB10-SCMH1-20-OROR 20 (40 μL) 200 μL
GRB10-SCMH1-20-ORGO 20 (40 μL) 200 μL
GRB10-SCMH1-20-ORAQ 20 (40 μL) 200 μL
GRB10-SCMH1-20-GORE 20 (40 μL) 200 μL
GRB10-SCMH1-20-GOOR 20 (40 μL) 200 μL
GRB10-SCMH1-20-GOGO 20 (40 μL) 200 μL
GRB10-SCMH1-20-GOGR 20 (40 μL) 200 μL
GRB10-SCMH1-20-GOAQ 20 (40 μL) 200 μL
GRB10-SCMH1-20-GRRE 20 (40 μL) 200 μL
GRB10-SCMH1-20-GROR 20 (40 μL) 200 μL
GRB10-SCMH1-20-GRGO 20 (40 μL) 200 μL
GRB10-SCMH1-20-GRGR 20 (40 μL) 200 μL
GRB10-SCMH1-20-GRAQ 20 (40 μL) 200 μL
GRB10-SCMH1-20-AQRE 20 (40 μL) 200 μL
GRB10-SCMH1-20-AQOR 20 (40 μL) 200 μL
GRB10-SCMH1-20-AQGO 20 (40 μL) 200 μL
GRB10-SCMH1-20-AQGR 20 (40 μL) 200 μL
GRB10-SCMH1-20-AQAQ 20 (40 μL) 200 μL

GRB10 Gene Summary

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]

Gene Name: Growth Factor Receptor Bound Protein 10

Chromosome: CHR7: 50657759 -50861159

Locus: 7p12.1

SCMH1 Gene Summary

The Scm Polycomb Group Protein Homolog 1 (SCMH1) gene is located on chr1 :41492870-41707815 at 1p34.2.

Gene Name: Scm Polycomb Group Protein Homolog 1

Chromosome: CHR1: 41492870 -41707815

Locus: 1p34.2

Gene Diseases

The GRB10 SCMH1 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.