GRB10-PIP4K2C Fusion FISH Probe
The GRB10-PIP4K2C Fusion FISH Probe is used to confirm a fusion of the GRB10 and PIP4K2C genes. The fusion of the GRB10 and PIP4K2C genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GRB10-PIP4K2C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-RERE | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-REOR | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-REGO | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-REGR | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-REAQ | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-ORRE | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-OROR | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-ORGO | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-ORAQ | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-GORE | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-GOOR | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-GOGO | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-GOGR | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-GOAQ | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-GRRE | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-GROR | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-GRGO | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-GRGR | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-GRAQ | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-AQRE | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-AQOR | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-AQGO | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-AQGR | 20 (40 μL) | 200 μL |
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| GRB10-PIP4K2C-20-AQAQ | 20 (40 μL) | 200 μL |
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GRB10 Gene Summary
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]
Gene Name: Growth Factor Receptor Bound Protein 10
Chromosome: CHR7: 50657759 -50861159
Locus: 7p12.1
PIP4K2C Gene Summary
The Phosphatidylinositol-5-phosphate 4-kinase Type 2 Gamma (PIP4K2C) gene is located on chr12 :57984941-57997211 at 12q13.3.
Gene Name: Phosphatidylinositol-5-phosphate 4-kinase Type 2 Gamma
Chromosome: CHR12: 57984941 -57997211
Locus: 12q13.3
Gene Diseases
The GRB10 PIP4K2C Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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