GRB10-CSTF3 Fusion FISH Probe
The GRB10-CSTF3 Fusion FISH Probe is used to confirm a fusion of the GRB10 and CSTF3 genes. The fusion of the GRB10 and CSTF3 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GRB10-CSTF3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-RERE | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-REOR | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-REGO | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-REGR | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-OROR | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-GORE | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-GROR | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| GRB10-CSTF3-20-AQAQ | 20 (40 μL) | 200 μL |
|
CSTF3 Gene Summary
The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Cleavage Stimulation Factor Subunit 3
Chromosome: CHR11: 33106129 -33183037
Locus: 11p13
GRB10 Gene Summary
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]
Gene Name: Growth Factor Receptor Bound Protein 10
Chromosome: CHR7: 50657759 -50861159
Locus: 7p12.1
Gene Diseases
The GRB10 CSTF3 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|