GPT2-HSD17B2 Fusion FISH Probe
The GPT2-HSD17B2 Fusion FISH Probe is used to confirm a fusion of the GPT2 and HSD17B2 genes. The fusion of the GPT2 and HSD17B2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GPT2-HSD17B2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-RERE | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-REOR | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-REGO | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-REGR | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-REAQ | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-ORRE | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-OROR | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-ORGO | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-ORAQ | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-GORE | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-GOOR | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-GOGO | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-GOGR | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-GOAQ | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-GRRE | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-GROR | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-GRGO | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-GRGR | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-GRAQ | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-AQRE | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-AQOR | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-AQGO | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-AQGR | 20 (40 μL) | 200 μL |
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| GPT2-HSD17B2-20-AQAQ | 20 (40 μL) | 200 μL |
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HSD17B2 Gene Summary
The Hydroxysteroid 17-beta Dehydrogenase 2 (HSD17B2) gene is located on chr16 :82068857-82132139 at 16q23.3.
Gene Name: Hydroxysteroid 17-beta Dehydrogenase 2
Chromosome: CHR16: 82068857 -82132139
Locus: 16q23.3
GPT2 Gene Summary
This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Gene Name: Glutamic--pyruvic Transaminase 2
Chromosome: CHR16: 46918307 -46965201
Locus: 16q11.2
Gene Diseases
The GPT2 HSD17B2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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