GPRC5A-NRG1 Fusion FISH Probe
The GPRC5A-NRG1 Fusion FISH Probe is used to confirm a fusion of the GPRC5A and NRG1 genes. The fusion of the GPRC5A and NRG1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GPRC5A-NRG1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-RERE | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-REOR | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-REGO | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-REGR | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-REAQ | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-ORRE | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-OROR | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-ORGO | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-ORAQ | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-GORE | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-GOOR | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-GOGO | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-GOGR | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-GOAQ | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-GRRE | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-GROR | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-GRGO | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-GRGR | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-GRAQ | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-AQRE | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-AQOR | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-AQGO | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-AQGR | 20 (40 μL) | 200 μL |
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| GPRC5A-NRG1-20-AQAQ | 20 (40 μL) | 200 μL |
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NRG1 Gene Summary
The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Apr 2016]
Gene Name: Neuregulin 1
Chromosome: CHR8: 31497267 -32600770
Locus: 8p12
GPRC5A Gene Summary
This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation. [provided by RefSeq, Jul 2008]
Gene Name: G Protein-coupled Receptor Class C Group 5 Member A
Chromosome: CHR12: 13043955 -13066600
Locus: 12p13.1
Gene Diseases
The GPRC5A NRG1 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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