GPR35-TIA1 Fusion FISH Probe
The GPR35-TIA1 Fusion FISH Probe is used to confirm a fusion of the GPR35 and TIA1 genes. The fusion of the GPR35 and TIA1 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GPR35-TIA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-RERE | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-REOR | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-REGO | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-REGR | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-REAQ | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-ORRE | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-OROR | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-ORGO | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-GORE | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-GOOR | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-GOGO | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-GOGR | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-GRRE | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-GROR | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-GRGO | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-GRGR | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-AQRE | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-AQOR | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-AQGO | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-AQGR | 20 (40 μL) | 200 μL |
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| GPR35-TIA1-20-AQAQ | 20 (40 μL) | 200 μL |
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GPR35 Gene Summary
The G Protein-coupled Receptor 35 (GPR35) gene is located on chr2 :241544824-241570676 at 2q37.3.
Gene Name: G Protein-coupled Receptor 35
Chromosome: CHR2: 241544824 -241570676
Locus: 2q37.3
TIA1 Gene Summary
The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene. [provided by RefSeq, May 2017]
Gene Name: TIA1 Cytotoxic Granule Associated RNA Binding Protein
Chromosome: CHR2: 70436575 -70475779
Locus: 2p13.3
Gene Diseases
The GPR35 TIA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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